Inhibitors of the transcribing enzymes

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Inhibitors of the Transcribing Enzymes

The enzymes which transcribe DNA synthesizing RNA (DNA-dependent RNA polymerases) have structural differences in eukaryotic and prokaryotic cells, as indicated by the fact, among others, that there are substances which inhibit their function selectively in prokaryotic cells (streptolydigin and the ansa antibiotics, such as rifamycins and streptovaricin) and in eukaryotic cells (-amanitin). Ansa...

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Inhibitors of Milk-curdling Enzymes

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Transcribing through the nucleosome.

The packaging of DNA into chromatin limits sequence accessibility, which affects all DNA-based processes including transcription. Indeed, the fundamental unit of chromatin, the nucleosome, presents a strong barrier to transcription in vitro. Since the discovery of the nucleosome barrier, the question of how the RNA polymerase II (Pol II) machinery overcomes nucleosomes at high speeds in vivo ha...

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A large number of studies dealing with phonology have focused their attention on phonological production at the expense of phonological perception which provides the foundation stone for phonological production. This study focuses on phonological perception at phonemic level. The purpose of the study is helping beginning learners improve their perception of the English phonemes which are confus...

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ژورنال

عنوان ژورنال: Pure and Applied Chemistry

سال: 1973

ISSN: 1365-3075,0033-4545

DOI: 10.1351/pac197335040383